Current Status of Adjuvant Therapy for Colorectal Cancer
نویسنده
چکیده
In the “Current Status of Adjuvant Therapy for Colorectal Cancer,” Dr. O’Connell provides important highlights of historical and recent developments in adjuvant treatment for colon and rectal cancer. In addition, he provides insight into the future directions of research for adjuvant therapy of cancer of the colon and rectum. As the review is thorough, we would like to expand upon a couple of areas including lymph node evaluation, changes to the staging system, and the use of molecular prognostic and predictive markers in future studies.
منابع مشابه
Current Status of Adjuvant Therapy for Colorectal Cancer
In the “Current Status of Adjuvant Therapy for Colorectal Cancer,” Dr. O’Connell provides important highlights of historical and recent developments in adjuvant treatment for colon and rectal cancer. In addition, he provides insight into the future directions of research for adjuvant therapy of cancer of the colon and rectum. As the review is thorough, we would like to expand upon a couple of a...
متن کاملCurrent Status of Adjuvant Therapy for Colorectal Cancer
In the “Current Status of Adjuvant Therapy for Colorectal Cancer,” Dr. O’Connell provides important highlights of historical and recent developments in adjuvant treatment for colon and rectal cancer. In addition, he provides insight into the future directions of research for adjuvant therapy of cancer of the colon and rectum. As the review is thorough, we would like to expand upon a couple of a...
متن کاملCurrent status of adjuvant therapy for colorectal cancer.
Adjuvant therapy with chemotherapy and/or radiation therapy in addition to surgery improves outcome for patients with high-risk carcinomas of the colon or rectum. For colon cancer, fluorouracil (5-FU) combined with leucovorin is a current standard of care that improves long-term survival. A recent European trial (MOSAIC) has documented significant improvement in 3-year disease-free survival whe...
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Survival from colorectal cancer has not improved over the last four decades despite advances in surgery and anaesthesia. The answer to the question whether adjuvant chemotherapy and radiotherapy will improve survival from the disease can only come from randomised, controlled trails. In the future, immunotherapy and gene therapy may be of benefit but these are still many years from the clinical ...
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